![]() The scope for automation means modern particle size analysis can often be a matter of loading the sample and hitting a button, which is an exciting prospect for pharmaceutical companies looking to scale their research. ![]() Semisolid drugs have some of the properties of solids and some of the properties of liquids, so understanding the size of the particles they contain is crucial in knowing how each particular product should be delivered to the human body. One example of this is the efficacy of ‘semisolid’ drugs, that are often used in ointments, creams, gels or lotions. ![]() Recognised for its capacity to reproduce results and size range spanning five orders of magnitude, laser diffraction has emerged as the technique of choice throughout the pharmaceutical industry where examining particle size is crucial in determining the performance of a product or process. Over the last twenty years, laser diffraction has, to a large extent, replaced traditional methods of particle size analysis, such as sieving and sedimentation (a previously common practice for granular material). The Role of Laser Diffraction in Particle Analysis As a technique that measures particle size distribution for both wet and dry dispersions, it offers many advantages, including a high level of precision, fast response, high potential for the repetition of results, and a wide measurable particle diameter range. Laser diffraction has emerged as one of the most important and effective techniques in the world of particle size analysis thanks to its fast, non-destructive properties, its suitability for a broad range of particle sizes, and its ability to be fully automated.
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